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Histamine Intolerance | Histamine Overload | Detox & Protocol

Histamine Intolerance | Histamine Overload | Detox & Protocol

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The histamine intolerance, or should we correctly call it the histamine overload health pack, contains a 90-day histamine detox using Toxaprevent, a histamine binder. You will receive the following in the histamine detox pack:

3 x Toxaprevent Medi Plus 30 Sachets (The purple box)
3 x Toxaprevent Medi Pure 180 Capsules (The red box)

The health pack contains our 90-day histamine intolerance & histamine overload detox and protocol, which mops up and removes excess Histamine.

How to use Toxaprevent for Histamine Intolerance

Toxaprevent binds and detoxes Histamine from the body, reversing symptoms associated with Histamine.

  • 1 hour before your first meal of the day. Take three x Toxaprevent Medi Pure Capsules (The red box) with 300ml of water 
  • 2 hours after your final meal of the day. Take three x Toxaprevent Medi Pure Capsules (red box) with 300ml water.
  • 2 hours after your final meal of the day. Mix one x Toxaprevent Medi Plus Sachet (The purple box) into 300ml water and drink.

Once Toxaprevent has attached, bound and mopped up the Histamine and other toxins, it's important to note. They can not be released and will leave the body when you pass your bowel movement.

How the Toxaprevent Medi Plus Sachets and Toxaprevent Medi Pure Capsules work to mop up Histamine

The Toxaprevent Medi Plus Sachets target the upper digestive tract, mouth, oesophagus, and stomach. The Toxaprevent Medi Plus Sachets bind and detox histamine quickly and safely from the upper digestive tract, reversing the symptoms associated with an overload of Histamine.

Meanwhile, the Toxaprevent Medi Pure Capsules target the lower digestive tract (intestines and colon). The Toxaprevent Medi Pure Capsules are designed to have a delayed release, meaning they pass through the stomach and open only once they reach the intestines, where they travel through mopping up Histamine and toxins, which trigger the release of Histamine from MAST Cells, such as moulds and mycotoxins.

The Toxaprevent Medi Pure Capsules and Toxaprevent Medi Plus Sachets work together, mopping up and removing excess Histamine from the body and emptying your histamine bucket. 

The natural and active ingredient in the Toxaprevet products is called MANC, which Stands for Modified Activated Natural Clinoptilolite. A safe and clean form of Zeolite Clinoptilolite. The MANC ingredient in Toxaprevent binds and detoxes Histamine from the gut and MAST cells, allowing your gut to heal and rebalancing your overreactive immune system.

In addition, Toxaprevent is scientifically backed to reverse, repair and strengthen the wall of your leaky gut. Toxaprevent is proven to reverse your histamine symptoms by removing the build-up of excess Histamine, which research shows is the cause of inflammation and histamine-related symptoms.

Why take Toxaprevent before bed 

We suggest taking Toxaprevent Medi Plus Sachets and Toxaprevent Medi Pure Capsules before bed, as they work alongside your body's circadian rhythm and natural detox cycle. As you sleep and rest, your body detoxes; taking Toxaprevent at night allows it to bind the toxins that are released as you sleep. This ensures that the gut can not reabsorb the released toxins. Histamine and the other toxins which trigger your MAST cells and histamine symptoms are removed alongside the Toxaprevent from the body via your stool and when you pass a bowel movement.

Toxaprevent Histamine Intolerance Detox Pack Ingredients

Each Toxaprevent Medi Plus Sachet contains 2400mg of MANC® particles (Modified Activated Natural Clinoptilolite) blended with 420mg calcium carbonate and 180mg magnesium carbonate.

Each Toxaprevent Medi Pure Capsule contains 400mg of MANC® (Modified Activated Natural Clinoptilolite), Capsule shell: Cellulose, and Gellan Gum.

Why Toxaprevent reverses histamine intolerance and histamine overload

Toxaprevent works on the root cause of your histamine symptoms, which is Histamine overload. Toxaprevent is a Histamine binder that detoxes the body and digestive tract from excess Histamine circulating throughout the body. Toxaprevent contains the activated and natural ingredient MANC, a clean, modified, and activated natural form of clinoptilolite zeolite. The Zeolite Clinoptilolite MANC particles in Toxaprevent bind and detox your body of Histamine. Research has shown us that Histamine causes inflammation in and around the body and is the cause of your histamine symptoms.

The Toxaprevent Medi Pure Capsules are specially coated, having a delayed release to work in the gut, i.e. intestines and the colon. The Toxaprevent Medi Plus Sachets bind and remove Histamine in the mouth, oesophagus, and stomach. In combination, the two products will effectively remove Histamine, reverse histamine symptoms and, most importantly, repair and reverse a leaky gut. 

Toxaprevent binds and removes Histamine from the body to provide you fast and effective relief from your histamine symptoms. Toxaprevent is proven to reverse and repair a leaky gut.

How Toxaprevent works

Toxaprevent contains the natural and active toxin binder MANC, which stands for Modified Activated Natural Clinoptilolite, the cleanest, safest and most natural form of Zeolite Clinoptilolite in the world. We activate our natural Clinoptilolite through a unique, scientifically proven process which optimises the particle size, ensuring that Toxaprevent stays only in the digestive tract and does not enter the liver or kidneys.

Toxaprevent has been granted and classified as a medical device:

  • Firstly, because it has been put through rigorous testing and has proof that it contains no toxins.
  • Secondly, Toxaprevent has been proven and patented to safely bind and detox toxins such as Histamine, heavy metals, aluminium, mould, mycotoxins, ochratoxins A & B, nitrosamines, agenic amines, ammonium, and other toxins from the body.
  • Thirdly, because Toxaprevent is inert, the particle is optimised to stay only in the digestive tract and is proven never to enter the bloodstream, liver or kidneys. This makes Toxaprevent the safest medical-grade Zeolite in the world.

We put our natural active ingredient through thorough research and testing, proving that it can effectively detox toxins which can pollute and overload our bodies. Toxaprevent reverses your histamine symptoms.

Excess Histamine, which cannot be broken down naturally by the body, leads to histamine intolerance and creates the histamine symptoms you are experiencing.

Once the natural active ingredient MANC particle binds to the Histamine, it simply detoxifies the toxins from your body via our natural bowel movements, relieving your symptoms and restoring your digestive health and histamine levels.

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Questions & Answers

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  • What are symptoms , a lot of women find there’s a connection, going through menopause ? I have read similar to my symptoms? But what is it I’m looking for regarding symptoms kind regards

    This is a tricky question to answer. To give you some background, Estrogen, when increased, triggers mast cells to release histamine and also prevents DAO (the enzyme in the gut which breaks down histamine) from breaking it down. This then triggers all the symptoms associated with histamine. However, when Estrogen decreases, this also causes the immune system to release histamine as it is trying to protect the body from what it 'thinks' is bad.

    The symptoms depend on the individual. They can be anything as simple as hot flushes, inflamed joints, hives, red skin, irritability, brain fog, and fatigue, to name a few. Histamine is linked with all these different conditions. As you start to use a histamine binder to mop up the histamine, you should see and feel some regulation in your histamine levels and symptoms.

  • I take eliquis 5mg morning and night. How do you suggest doing the protocol alongside this medication? I also take an L glutamine powder twice a day, 30 minutes before eating. It has helped greatly to sooth my gut. Do you suggest holding off on this during the protocol or combining?

    So you can take the Toxaprevent Medi Pure Capsules two hours after your morning medication. We would then suggest taking the Toxaprevent Medi Plus Sachets and Capsules together 2 hours after your lunch. Toxaprevent does not interfere with vitamins, minerals or supplements. 

    We hope this helps. 

  • Hi. I am using 0,5 mg Rivotril and Orfiril 300 mg x2. Is this save for me to use? I have chronic urticatia and are on Xolair injection every 4 weeks. Is this product save for me to use?.

    Yes, as long as you leave a two hour gap between medication and the Toxaprevent there is no issue. Even with Xolair injection, please wait two hours then take Toxaprevent.

  • Is it worth taking probiotics and prebiotics at the same time as Toxaprevent or is it better to wait until after the histamine detox?

    So it depends on where your Gut is. You can take both, but we would say wait until at least 8/10 weeks of taking Toxaprevent and following the histamine intolerance protocol if there is dysbiosis, we do not want to trigger a further histamine response or cause any inflammation. We want to heal the gut and then begin repopulating!

  • I have been on a low histamine diet for 2 years and am better than I was when I started but I still can’t eat medium to high histamine foods without reacting. I live in the U.S. so your product is a lot of $, plus high shipping. and I’m sensitive and reacted bad to another brand of zeolite. Do you sale samples or small bottles so I can see if it works for me. Thank you!

    Hey, so Toxaprevent is shipped from our US warehouse so we pay all the shipping and duties into the USA. It's likely you reacted to something else within the Zeolite. If you drop us an email: and ask for Dilly I can talk and work with you through this.

  • Can you do the histamine protocol if on HRT, as I use oestrogen patch and take progesterone tablet at night? Thank you.

    Yes you can. Toxaprevent does not close the blood barrier, and does not enter the liver or kidneys to be processed, because of this it will not interfere with the oestrogen patch. With the progesterone tablet at night, you would need to leave a two hour gap. Our best advice would be take your Toxaprevent in the morning and afternoon then continue taking your progesterone tablet at night.

  • I am a 64 year old male, diagnosed with LPR in October last year, Burning Mouth Syndrome followed in February of this year. I have read a great deal since developing these two horrendous conditions and it does appear that LPR can/does cause BMS...could your product help me and if so how? thanks

    Both LPR and Burning Mouth Syndrome are linked not only with Histamine but also Ammonium. When our immune system is overreactive it releases histamine which is what triggers the burning sensation in the mouth. Excess histamine also triggers the Histamine 2 Receptor which is located in the gut. This receptor's one use is for acid regulation.

    Toxaprevent binds directly to the histamine and ammonium in the body and detoxes them from the body when you pass stool. Both the histamine and ammonium alongside the Toxaprevent are removed from the body! Therefore bringing not only your immune system back into balance but also reducing your histamine symptoms.

    We would recommend following the Histamine Detox Protocol and in addition, we would highly recommend the Dentura Med Sensitive Toothpaste which contains the same ingredient as Toxaprevent but is designed to detox the mouth!

  • Burning mouth syndrome: is this protocol appropriate and, if so, what is your reported success rate? Also experiencing extreme GI symptoms, which may also be HI intolerance/overload related.

    Yes it is! The protocol is designed to reduce your histamine load, and support in reversing the immune response. However, with Burning Mouth Syndrome we also recommend using our toothpaste as it is designed to bind to histamine and reduce inflammation in the mouth. You can also use the Toxaprevent Halistop Chewables as they are designed to bind to histamine alongside sulphur and mycotoxins in the mouth. Alongside the Histamine Overload protocol it is very powerful in reversing your symptoms.

  • Is it worth using the topical treatments alongside the 3 month protocol for someone who is experiencing intense itching?

    Yes. The Toxaprevent Skin Suspension is awesome as it opens up the pores of the skin and detoxes histamine from underneath the surface of the skin. However, we don't recommend using it straight away. Follow the histamine protocol for at least 4 weeks before introducing the suspension. You have to note the Suspension is pulling the histamine to the surface of the skin so your skin may get a little bit irrirated as your body detoxes.

    Please note, once you open the suspension use it daily until you finish the tube. You can wash and re-use the medical foil (plastic foil) and use it as and when needed.

  • How quickly can someone expect some relief from intense itching in the morning after starting this treatment?

    It depends on your histamine levels. With most after 6 weeks of using Toxaprevent for your intense itching you should break out of the histamine cycle and the intense itching will stop. However, for some it could take a little longer. It all depends on your histamine, as your body needs support in breaking down and bringing it back in to balance. It also depends on your histamine triggers, for example if stress is a major trigger then working on reducing stress will help. If food is a trigger, then its a case of have you removed the specific foods.

    It can take a short amount of time, but you will get better as the histamine is detoxed from your body and your immune system goes back into balance.